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  3. Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【

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问题    Many people are disturbed by the genetic diversity of cancers — an inevitable consequence of random evolution. Cancer therapies【C1】______be applied fairly randomly or carelessly, but nowadays many believe that effective therapies need to be【C2】______and tailored to genetic faults in each individual’s cancer.
   However, a personalized treatment disregards the most fundamental reason why it is difficult to cure cancers【C3】______: cancer cells adapt and evolve【C4】______treatment. Even drugs that are initially effective often have a【C5】______diminishing effect, as the biological systems blocked by the treatment spontaneously compensate【C6】______re-routing the cancer cells’ internal wiring,【C7】______the cancer’s ability to spread. To use an【C8】______, traffic hot spots in towns can cause major traffic jams, but smart drivers will quickly find other short cuts. Then, in the absence of "short cuts", evolution【C9】______: naturally arising mutant cancer cells that are【C10】______the targeted drug rapidly outgrow their disabled siblings and cancer comes back.
【C5】
选项 A、hardly
B、progressively
C、promptly
D、perpetually
答案B
解析 progressively：程度逐渐增强，渐进式地，所以该句中的have a progressively diminishing effect的意义是“效果越来越差”。药物的疗效通常不可能瞬间减弱，要有个过程，也不可能永远减弱，无止无休。
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