Honda’s worldwide output increased to ______ in 2005.

Honda Motor Co., Ltd.in 2005 set calendar year records for both worldwide and overseas production, due largely to increased output in North America and Asia.Honda’s overseas production increased 10.8% compared with 2004 to 2,147,997. It marked the ninth consecutive year that volumes exceeded the previous year. Worldwide output jumped 7.2% to 3,409,991, also the ninth straight year of gains. Production in Japan increased 1.6% in 2005 to 1,261,994, due largely to a rise in output for exports. Honda’s sales in Japan totaled 714, 030 units last year, a 3.9% decline from 2004, due to decreased demand for minivehicles, passenger cars and light trucks.

There are two primary ways that genes can be used to treat disease. The first is gene therapy, in which one or more genes are injected into the patient to replace those that are absent or not working properly. This approach has been used to treat heart disease and many forms of cancer. The second way to exploit genes to treat disease is known as small-molecule therapy. In this approach, a small-molecule (that is a drug) is given to the patient to modify the function of one or more genes in the body.