_____before, his first performance for the amateur dramatic group was a success.

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问题 _____before, his first performance for the amateur dramatic group was a success.

选项 A、Though having never acted
B、As he had never acted
C、Despite he had never acted
D、In spite of his never having acted

答案D

解析 in spite of意为“尽管，虽然”，后接名词或名词性短语，引导出让步状语。选项A没有主语或逻辑主语，选项B是原因状语从句，选项C的despite不能引导状语从句，因为它是个介词。

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